The center dot is a carbon atom. To add bonds, choose a bond type and click the central atom. To replace atoms, choose an element and click the atom you would like to replace.
This tool uses atom pair descriptors with the Tanimoto similarity metric. Stereoisomers will appear as separate hits, with identical scores. The "Search cluster database" option can limit search
hits to only gene clusters with manually confirmed annotations, or also include
a large set of machine annotated gene clusters, which may contain errors.